PTCD1, pentatricopeptide repeat domain 1

PTCD1, pentatricopeptide repeat domain 1

• This gene encodes a mitochondrial protein that binds leucine tRNAs and other mitochondrial RNAs and plays a role in the regulation of translation. Increased expression of this gene results in decreased mitochondrial leucine tRNA levels. Naturally occurring read-through transcription exists between upstream ATP5J2 (ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2) and this gene. [provided by RefSeq, Aug 2015]

• Gene Synonyms (pentatricopeptide repeat-containing protein 1, mitochondrial,)
• NCBI Gene ID: 26024
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A4D273
  UNIPROT ID#>>O75127
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

pentatricopeptide repeat domain 1 interacts with:

• apolipoprotein B mRNA editing enzyme catalytic subunit 3D
  aurora kinase A interacting protein 1
  caspase recruitment domain family member 10
  DEAD-box helicase 28
  FKBP prolyl isomerase 7
  gem nuclear organelle associated protein 4
  LEO1 homolog, Paf1/RNA polymerase II complex component
  lin-28 homolog A
  lin-28 homolog B
  MAPK associated protein 1
  mitochondrial ribosomal protein L39
  mitochondrial ribosomal protein L4
  mitochondrial ribosomal protein L50
  mitochondrial ribosomal protein S5
  mitochondrial rRNA methyltransferase 1
  NFKB inhibitor delta
  potassium channel tetramerization domain containing 10
  RIO kinase 1
  RNA binding motif protein 42
  RNA binding motif protein X-linked
  transformer 2 alpha homolog
  tRNA methyltransferase 61B
  zinc finger protein 324B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.