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STEAP2, STEAP2 metalloreductase

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STEAP2, STEAP2 metalloreductase

  • This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

  • Gene Synonyms (metalloreductase STEAP2, STEAP family member 2, metalloreductase, SixTransMembrane Protein of Prostate 1, prostate cancer-associated protein 1, protein up-regulated in metastatic prostate cancer, protein upregulated in metastatic prostate cancer, six transmembrane epithelial antigen of the prostate 2, six-transmembrane epithelial antigen of prostate 2, IPCA1, PCANAP1, PUMPCn, STAMP1, STMP,)
  • NCBI Gene ID: 261729
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q6YPB2
    UNIPROT ID#>>B3KS24
    UNIPROT ID#>>Q8NFT2
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

STEAP2 metalloreductase interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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