- Gene Overview
- Interaction Network
- Sequence Verification
STEAP2, STEAP2 metalloreductase
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This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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Gene Synonyms (metalloreductase STEAP2, STEAP family member 2, metalloreductase, SixTransMembrane Protein of Prostate 1, prostate cancer-associated protein 1, protein up-regulated in metastatic prostate cancer, protein upregulated in metastatic prostate cancer, six transmembrane epithelial antigen of the prostate 2, six-transmembrane epithelial antigen of prostate 2, IPCA1, PCANAP1, PUMPCn, STAMP1, STMP,)
- NCBI Gene ID:
261729
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q6YPB2
UNIPROT ID#>>B3KS24
UNIPROT ID#>>Q8NFT2
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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STEAP2 metalloreductase interacts with:
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