TIMM8B, translocase of inner mitochondrial membrane 8 homolog B

TIMM8B, translocase of inner mitochondrial membrane 8 homolog B

• This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.[provided by RefSeq, Aug 2009]

• Gene Synonyms (mitochondrial import inner membrane translocase subunit Tim8 B, DDP-like protein, deafness dystonia protein 2, DDP2, TIM8B,)
• NCBI Gene ID: 26521
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y5J9
  UNIPROT ID#>>G3XAN8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

translocase of inner mitochondrial membrane 8 homolog B interacts with:

• aurora kinase A interacting protein 1
  chromosome 15 open reading frame 48
  coenzyme Q10B
  cytochrome c oxidase assembly factor COX14
  EGF like domain multiple 8
  egl-9 family hypoxia inducible factor 3
  forkhead box I2
  kinesin light chain 2
  N-alpha-acetyltransferase 50, NatE catalytic subunit
  plasminogen receptor with a C-terminal lysine
  sideroflexin 1
  solute carrier family 15 member 3
  TNFAIP3 interacting protein 2
  ybeY metalloendoribonuclease

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.