PCLO, piccolo presynaptic cytomatrix protein

PCLO, piccolo presynaptic cytomatrix protein

• The protein encoded by this gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

• Gene Synonyms (protein piccolo, aczonin, ACZ, PCH3,)
• NCBI Gene ID: 27445
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y6V0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

piccolo presynaptic cytomatrix protein interacts with:

• centrosomal protein 72
  developmental pluripotency associated 4
  GIT ArfGAP 1
  potassium channel tetramerization domain containing 10
  ring finger protein 123

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.