PIGW, phosphatidylinositol glycan anchor biosynthesis class W

PIGW, phosphatidylinositol glycan anchor biosynthesis class W

• The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017]

• Gene Synonyms (phosphatidylinositol-glycan biosynthesis class W protein, Gwt1, HPMRS5,)
• NCBI Gene ID: 284098
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7Z7B1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylinositol glycan anchor biosynthesis class W interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.