- Gene Overview
- Interaction Network
- Sequence Verification
FBXW12, F-box and WD repeat domain containing 12
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Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
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Gene Synonyms (F-box/WD repeat-containing protein 12, F-box and WD-40 domain protein 12, F-box and WD-40 domain-containing protein 12, F-box only protein 35, F-box- and WD40-repeat-containing protein, FBW12, FBXO12, FBXO35,)
- NCBI Gene ID:
285231
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q6X9E4
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
F-box and WD repeat domain containing 12 interacts with:
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this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
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