RGCC, regulator of cell cycle

RGCC, regulator of cell cycle

• This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq, Jul 2008]

• Gene Synonyms (regulator of cell cycle RGCC, response gene to complement 32 protein, C13orf15, RGC-32, RGC32, bA157L14.2,)
• NCBI Gene ID: 28984
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H4X1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

regulator of cell cycle interacts with:

• cysteinyl-tRNA synthetase 2, mitochondrial
  talin 2
  TNF receptor associated factor 7

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.