VPREB3, V-set pre-B cell surrogate light chain 3

VPREB3, V-set pre-B cell surrogate light chain 3

• The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas. [provided by RefSeq, Apr 2015]

• Gene Synonyms (pre-B lymphocyte protein 3, pre-B lymphocyte 3, pre-B lymphocyte gene 3, 8HS20, N27C7-2,)
• NCBI Gene ID: 29802
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UKI3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

V-set pre-B cell surrogate light chain 3 interacts with:

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