HCFC2, host cell factor C2

HCFC2, host cell factor C2

• This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008]

• Gene Synonyms (host cell factor 2, C2 factor, HCF-2, HCF2,)
• NCBI Gene ID: 29915
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y5Z7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

host cell factor C2 interacts with:

• biorientation of chromosomes in cell division 1 like 1
  CXXC finger protein 1
  SET nuclear oncogene
  THAP domain containing 2
  tubulin beta 8 class VIII

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.