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OSGIN1, oxidative stress induced growth inhibitor 1

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OSGIN1, oxidative stress induced growth inhibitor 1

  • This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011]

  • Gene Synonyms (oxidative stress-induced growth inhibitor 1, BMSC-derived growth inhibitor, bone marrow stromal cell-derived growth inhibitor, ovary, kidney and liver protein 38, pregnancy-induced growth inhibitor OKL38, BDGI, OKL38,)
  • NCBI Gene ID: 29948
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q9UJX0
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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