HOXC8, homeobox C8

HOXC8, homeobox C8

• This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. [provided by RefSeq, Jul 2008]

• Gene Synonyms (homeobox protein Hox-C8, Hox-3.1, mouse, homolog of, homeo box 3A, homeo box C8, homeobox protein Hox-3A, HOX3, HOX3A,)
• NCBI Gene ID: 3224
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P31273
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

homeobox C8 interacts with:

• ADAMTS like 4
  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
  ankyrin repeat and sterile alpha motif domain containing 1A
  basic leucine zipper nuclear factor 1
  BTG anti-proliferation factor 2
  calcium dependent secretion activator
  CCM2 scaffold protein
  centrosomal protein 70
  chromosome 1 open reading frame 109
  chromosome 11 open reading frame 1
  chromosome 19 open reading frame 54
  cysteine rich tail 1
  DAZ interacting zinc finger protein 3
  geminin DNA replication inhibitor
  glutathione S-transferase omega 2
  golgin A6 family like 9
  heat shock transcription factor 2 binding protein
  HESX homeobox 1
  homeobox and leucine zipper encoding
  homeobox D3
  IKAROS family zinc finger 3
  Jun proto-oncogene, AP-1 transcription factor subunit
  keratin 34
  keratin 35
  keratin 36
  keratin 40
  keratin associated protein 10-7
  keratin associated protein 10-8
  keratin associated protein 10-9
  keratin associated protein 1-1
  keratin associated protein 11-1
  keratin associated protein 12-1
  keratin associated protein 1-3
  keratin associated protein 13-3
  keratin associated protein 19-2
  keratin associated protein 6-1
  keratin associated protein 6-2
  keratin associated protein 6-3
  keratin associated protein 8-1
  keratinocyte proline rich protein
  KH domain containing 1
  LDOC1 regulator of NFKB signaling
  LIM homeobox 2
  LIM homeobox 3
  low density lipoprotein receptor adaptor protein 1
  LRP2 binding protein
  lysine methyltransferase 2A
  mesenchyme homeobox 1
  mesenchyme homeobox 2
  methyltransferase like 15
  mitogen-activated protein kinase 8 interacting protein 1
  mitogen-activated protein kinase 8 interacting protein 2
  msh homeobox 1
  NAD synthetase 1
  NBPF member 19
  NFKB inhibitor delta
  nidogen 2
  notch 2 N-terminal like A
  Opa interacting protein 5
  paired box 5
  paired box 6
  paired box 8
  PBX homeobox 1
  PBX homeobox 2
  PBX homeobox 4
  peroxisome proliferator activated receptor alpha
  phosphodiesterase 4D interacting protein
  phospholipase A2 group X
  pleckstrin homology and RhoGEF domain containing G4
  potassium channel tetramerization domain containing 9
  POU class 2 homeobox associating factor 1
  POU class 6 homeobox 2
  PR/SET domain 14
  PR/SET domain 6
  prefoldin subunit 5
  RANBP2-type and C3HC4-type zinc finger containing 1
  RNA binding protein, mRNA processing factor
  SLAIN motif family member 1
  SMAD family member 1
  SMAD family member 4
  SMAD family member 6
  sorting nexin 17
  TBC1 domain family member 1
  T-box transcription factor 19
  T-box transcription factor 22
  tektin 4
  tensin 2
  thyroid hormone receptor interactor 6
  TNF receptor associated factor 1
  tribbles pseudokinase 3
  tripartite motif containing 27
  tripartite motif containing 42
  TSC complex subunit 1
  ubiquitin specific peptidase 54
  VENT homeobox
  WW domain containing oxidoreductase
  ZFP90 zinc finger protein
  zinc finger matrin-type 5
  zinc finger protein 34
  zinc finger RANBP2-type containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.