FREM2, FRAS1 related extracellular matrix 2

FREM2, FRAS1 related extracellular matrix 2

• This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Apr 2014]

• Gene Synonyms (CRYPTOP, FRASRS2, FRAS1-related extracellular matrix protein 2, ECM3 homolog, FRAS1 related extracellular matrix protein 2,)
• NCBI Gene ID: 341640
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5SZK8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FRAS1 related extracellular matrix 2 interacts with:

• pregnancy specific beta-1-glycoprotein 8
  X antigen family member 1A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.