ITGAD, integrin subunit alpha D

ITGAD, integrin subunit alpha D

• This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Gene Synonyms (ADB2, CD11D, integrin alpha-D, CD11 antigen-like family member D, beta-2 integrin alphaD subunit, leukointegrin alpha D,)
• NCBI Gene ID: 3681
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q59H14
  UNIPROT ID#>>Q13349
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

integrin subunit alpha D interacts with:

• integrin subunit beta 2
  ribosomal RNA processing 1 homolog B (S. cerevisiae)
  SHANK associated RH domain interactor
  vascular cell adhesion molecule 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.