THEMIS, thymocyte selection associated

THEMIS, thymocyte selection associated

• This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

• Gene Synonyms (C6orf190, C6orf207, GASP, SPOT, TSEPA, protein THEMIS, GRB2-associated protein, signaling phosphoprotein specific for T cells, thymocyte selection pathway associated, thymocyte-expressed molecule involved in selection,)
• NCBI Gene ID: 387357
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N1K5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

thymocyte selection associated interacts with:

• POTE ankyrin domain family member F

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.