KITLG, KIT ligand

KITLG, KIT ligand

• This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (DCUA, DFNA69, FPH2, FPHH, KL-1, Kitl, MGF, SCF, SF, SHEP7, SLF, kit ligand, c-Kit ligand, familial progressive hyperpigmentation 2, mast cell growth factor, steel factor, stem cell factor,)
• NCBI Gene ID: 4254
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RBF5
  UNIPROT ID#>>P21583
  UNIPROT ID#>>A0A024RBC0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

KIT ligand interacts with:

• ATPase phospholipid transporting 8B2
  C-type lectin domain containing 11A
  kelch domain containing 10
  KIT ligand
  phosphatidylinositol glycan anchor biosynthesis class U
  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
  solute carrier family 22 member 18
  ubiquitin conjugating enzyme E2 V1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.