MYH1, myosin heavy chain 1

MYH1, myosin heavy chain 1

• Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. [provided by RefSeq, Jul 2008]

• Gene Synonyms (HEL71, MYHSA1, MYHa, MyHC-2X/D, MyHC-2x, myosin-1, epididymis luminal protein 71, myHC-IIx/d, myosin heavy chain 2x, myosin heavy chain IIx/d, myosin heavy chain, skeletal muscle, adult 1, myosin, heavy chain 1, skeletal muscle, adult, myosin, heavy polypeptide 1, skeletal muscle, adult,)
• NCBI Gene ID: 4619
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P12882
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

myosin heavy chain 1 interacts with:

• argonaute RISC catalytic component 2
  aurora kinase C
  coiled-coil domain containing 125
  estrogen related receptor, beta
  kinesin light chain 3
  phosphatidylinositol 3-kinase catalytic subunit type 3
  protein phosphatase methylesterase 1
  pyruvate dehydrogenase kinase 1
  regulating synaptic membrane exocytosis 1
  ring finger protein 123
  sortilin 1
  staufen double-stranded RNA binding protein 1
  synaptotagmin binding cytoplasmic RNA interacting protein
  TLE family member 3, transcriptional corepressor
  transmembrane protein 260
  tropomyosin 1
  ubiquitin C
  VPS26, retromer complex component B
  WW domain containing oxidoreductase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.