NDUFB2, NADH:ubiquinone oxidoreductase subunit B2

NDUFB2, NADH:ubiquinone oxidoreductase subunit B2

• The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I. [provided by RefSeq, Jul 2008]

• Gene Synonyms (AGGG, CI-AGGG, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial, NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa, NADH-ubiquinone oxidoreductase AGGG subunit, complex I AGGG subunit, complex I-AGGG,)
• NCBI Gene ID: 4708
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95178
  UNIPROT ID#>>A4D1T5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NADH:ubiquinone oxidoreductase subunit B2 interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  cell division cycle 7
  integrator complex subunit 5
  mediator complex subunit 23
  mediator complex subunit 24
  methyltransferase like 17
  NADH:ubiquinone oxidoreductase subunit B7
  nucleoporin 54
  phosphofructokinase, muscle
  phosphoglycerate kinase 1
  proteasome 26S subunit, ATPase 6
  proteasome 26S subunit, non-ATPase 4
  RTF1 homolog, Paf1/RNA polymerase II complex component
  succinate dehydrogenase complex subunit C
  ubiquinol-cytochrome c reductase binding protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.