NFATC3, nuclear factor of activated T cells 3

NFATC3, nuclear factor of activated T cells 3

• The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010]

• Gene Synonyms (NF-AT4c, NFAT4, NFATX, nuclear factor of activated T-cells, cytoplasmic 3, NF-ATc3, T cell transcription factor NFAT4, nuclear factor of activated T-cells c3 isoform IE-Xa, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3,)
• NCBI Gene ID: 4775
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B5B2S1
  UNIPROT ID#>>B5B2S0
  UNIPROT ID#>>Q12968
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear factor of activated T cells 3 interacts with:

• BICD cargo adaptor 2
  centrosomal protein 128
  egl-9 family hypoxia inducible factor 3
  mitogen-activated protein kinase 8
  mitogen-activated protein kinase 9
  nuclear receptor coactivator 3
  nuclear RNA export factor 1
  serine hydroxymethyltransferase 2
  serine/threonine kinase 40
  SUFU negative regulator of hedgehog signaling
  transcription termination factor 1
  vir like m6A methyltransferase associated
  zinc finger MIZ-type containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.