NHS, NHS actin remodeling regulator

NHS, NHS actin remodeling regulator

• This gene encodes a protein containing four conserved nuclear localization signals. The encoded protein functions in eye, tooth, craniofacial and brain development, and it can regulate actin remodeling and cell morphology. Mutations in this gene have been shown to cause Nance-Horan syndrome, and also X-linked cataract-40. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2014]

• Gene Synonyms (CTRCT40, CXN, SCML1, Nance-Horan syndrome protein, Nance-Horan syndrome (congenital cataracts and dental anomalies), congenital cataracts and dental anomalies protein,)
• NCBI Gene ID: 4810
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6T4R5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NHS actin remodeling regulator interacts with:

• abl interactor 1
  BAG cochaperone 6
  centromere protein U
  myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1
  NPR2 like, GATOR1 complex subunit
  OTU domain containing 5
  protein tyrosine phosphatase receptor type U
  ribophorin I
  ring finger protein 138
  sestrin 2
  small glutamine rich tetratricopeptide repeat containing beta
  sortilin 1
  synaptotagmin binding cytoplasmic RNA interacting protein
  tubulin, gamma 1
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  ubiquitin specific peptidase 43
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.