NTF3, neurotrophin 3

NTF3, neurotrophin 3

• The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008]

• Gene Synonyms (HDNF, NGF-2, NGF2, NT-3, NT3, neurotrophin-3, nerve growth factor 2, neurotrophic factor,)
• NCBI Gene ID: 4908
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P20783
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

neurotrophin 3 interacts with:

• glycogen phosphorylase B
  glycogen phosphorylase L
  MAD2L1 binding protein
  neurotrophic receptor tyrosine kinase 1
  neurotrophic receptor tyrosine kinase 2
  neurotrophic receptor tyrosine kinase 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.