CHST11, carbohydrate sulfotransferase 11

CHST11, carbohydrate sulfotransferase 11

• The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

• Gene Synonyms (carbohydrate sulfotransferase 11, C4S-1, IgH/CHST11 fusion, carbohydrate (chondroitin 4) sulfotransferase 11, chondroitin 4-O-sulfotransferase 1, C4ST, C4ST-1, C4ST1, HSA269537, OCBMD,)
• NCBI Gene ID: 50515
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RBL0
  UNIPROT ID#>>Q9NPF2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

carbohydrate sulfotransferase 11 interacts with:

• solute carrier family 2 member 12
  stromal cell derived factor 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.