KCNK4, potassium two pore domain channel subfamily K member 4

KCNK4, potassium two pore domain channel subfamily K member 4

• This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802. [provided by RefSeq, Nov 2015]

• Gene Synonyms (potassium channel subfamily K member 4, K2P4.1 potassium channel, TWIK-related arachidonic acid-stimulated potassium channel protein, potassium channel, subfamily K, member 4, potassium channel, two pore domain subfamily K, member 4, two pore K(+) channel KT4.1, two pore K+ channel KT4.1, two pore potassium channel KT4.1, FHEIG, K2p4.1, TRAAK, TRAAK1,)
• NCBI Gene ID: 50801
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NYG8
  UNIPROT ID#>>Q2YDA1
  UNIPROT ID#>>A0A024R5C7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium two pore domain channel subfamily K member 4 interacts with:

• ORMDL sphingolipid biosynthesis regulator 1

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