MRPS18C, mitochondrial ribosomal protein S18C

MRPS18C, mitochondrial ribosomal protein S18C

• Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008]

• Gene Synonyms (28S ribosomal protein S18c, mitochondrial, 28S ribosomal protein S18-1, mitochondrial, mitochondrial ribosomal protein S18-1, mitochondrial small ribosomal subunit protein bS18c, mitochondrial small ribosomal subunit protein bS18m, mitochondrial small ribosomal subunit protein bS18m-C, CGI-134, MRP-S18-1, MRP-S18-c, MRPS18-1, S18mt-c, mrps18-c,)
• NCBI Gene ID: 51023
• Species: Homo sapiens (Human)
• UNIPROT ID#>>D6RCM2
  UNIPROT ID#>>Q9Y3D5
  UNIPROT ID#>>D6RE70
  UNIPROT ID#>>A0A024RDH9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitochondrial ribosomal protein S18C interacts with:

• aurora kinase A interacting protein 1
  La ribonucleoprotein 7, transcriptional regulator
  methylphosphate capping enzyme
  mitochondrial ribosomal protein S11
  mitochondrial ribosomal protein S2
  mitochondrial ribosomal protein S34
  mitochondrial ribosomal protein S5
  mitochondrial ribosomal protein S6
  nucleolar protein 12
  protein phosphatase targeting COQ7
  tRNA methyltransferase 10B
  zinc finger protein 707

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.