GP6, glycoprotein VI platelet

GP6, glycoprotein VI platelet

• This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

• Gene Synonyms (platelet glycoprotein VI, glycoprotein 6, platelet collagen receptor, BDPLT11, GPIV, GPVI,)
• NCBI Gene ID: 51206
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HCN6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glycoprotein VI platelet interacts with:

• neutrophil cytosolic factor 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.