TMCO1, transmembrane and coiled-coil domains 1

TMCO1, transmembrane and coiled-coil domains 1

• This locus encodes a transmembrane protein. Mutations at this locus have been associated with craniofacial dysmorphism, skeletal anomalies, and cognitive disability. Mutations at this locus have also been associated with open angle glaucoma blindness. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]

• Gene Synonyms (calcium load-activated calcium channel, CLAC channel, Ca(2+) load-activated Ca(2+) channel, putative membrane protein, transmembrane and coiled-coil domain-containing protein 1, transmembrane and coiled-coil domains 4, xenogeneic cross-immune protein PCIA3, HP10122, PCIA3, PNAS-136, TMCC4,)
• NCBI Gene ID: 54499
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z591
  UNIPROT ID#>>Q9UM00
  UNIPROT ID#>>J9JIE6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transmembrane and coiled-coil domains 1 interacts with:

• anaphase promoting complex subunit 2
  cullin associated and neddylation dissociated 1
  dual specificity phosphatase 22
  dynein, axonemal assembly factor 5
  egl-9 family hypoxia inducible factor 3
  heterogeneous nuclear ribonucleoprotein F
  hypoxia inducible factor 1 subunit alpha inhibitor
  kinesin light chain 4
  limb development membrane protein 1 like
  RAB1B, member RAS oncogene family
  serine incorporator 1
  tectonic family member 2
  transmembrane protein 63B
  unc-93 homolog B1, TLR signaling regulator
  Yip1 domain family member 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.