XAF1, XIAP associated factor 1

XAF1, XIAP associated factor 1

• This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

• Gene Synonyms (XIAP-associated factor 1, BIRC4-binding protein, BIRC4BP, HSXIAPAF1, XIAPAF1,)
• NCBI Gene ID: 54739
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6GPH4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

XIAP associated factor 1 interacts with:

• baculoviral IAP repeat containing 7
  leucine rich repeat and sterile alpha motif containing 1
  ring finger protein 114
  ring finger protein 166
  tripartite motif containing 50
  tripartite motif containing 54
  tripartite motif family like 2
  UBX domain protein 2B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.