TRIT1, tRNA isopentenyltransferase 1

TRIT1, tRNA isopentenyltransferase 1

• This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015]

• Gene Synonyms (tRNA dimethylallyltransferase, IPP transferase, isopentenyl-diphosphate:tRNA isopentenyltransferase, tRNA dimethylallyltransferase, mitochondrial, tRNA isopentenylpyrophosphate transferase, COXPD35, GRO1, IPPT, IPT, IPTase, MOD5, hGRO1,)
• NCBI Gene ID: 54802
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q53F11
  UNIPROT ID#>>Q9H3H1
  UNIPROT ID#>>Q3T7C7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tRNA isopentenyltransferase 1 interacts with:

• SET and MYND domain containing 3
  Src homology 2 domain containing E

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.