BEST2, bestrophin 2

BEST2, bestrophin 2

• This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008]

• Gene Synonyms (bestrophin-2, VMD2-like gene 1, vitelliform macular dystrophy 2-like 1, vitelliform macular dystrophy 2-like protein 1, VMD2L1,)
• NCBI Gene ID: 54831
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NFU1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

bestrophin 2 interacts with:

• DnaJ heat shock protein family (Hsp40) member C30
  major facilitator superfamily domain containing 5
  RFT1 homolog
  solute carrier family 66 member 2
  transmembrane protein 128
  transmembrane protein 60
  unc-93 homolog B1, TLR signaling regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.