- Gene Overview
- Interaction Network
- Sequence Verification
POLR2J3, RNA polymerase II subunit J3
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This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq, Jul 2008]
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Gene Synonyms (POLR2J2, RPB11b1, RPB11b2, DNA-directed RNA polymerase II subunit RPB11-b2, DNA-directed RNA polymerase II subunit 11, DNA-directed RNA polymerase II subunit J2, DNA-directed RNA polymerase II subunit J3, DNA-directed RNA polymerase II subunit RPB11-b1, RNA polymerase II subunit B11-b1, RNA polymerase II subunit B11-b2, polymerase (RNA) II (DNA directed) polypeptide J3, polymerase (RNA) II subunit J3,)
- NCBI Gene ID:
548644
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q9GZM3
UNIPROT ID#>>A0A0B4J2F8
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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RNA polymerase II subunit J3 interacts with:
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