MTARC2, mitochondrial amidoxime reducing component 2

MTARC2, mitochondrial amidoxime reducing component 2

• The protein encoded by this gene is an enzyme found in the outer mitochondrial membrane that reduces N-hydroxylated substrates. The encoded protein uses molybdenum as a cofactor and cytochrome b5 type B and NADH cytochrome b5 reductase as accessory proteins. One type of substrate used is N-hydroxylated nucleotide base analogues, which can be toxic to a cell. Other substrates include N(omega)-hydroxy-L-arginine (NOHA) and amidoxime prodrugs, which are activated by the encoded enzyme. Multiple transcript variants encoding the different isoforms have been found for this gene. [provided by RefSeq, Sep 2016]

• Gene Synonyms (mitochondrial amidoxime reducing component 2, MOCO sulphurase C-terminal domain containing 2, MOSC domain-containing protein 2, mitochondrial, moco sulfurase C-terminal domain-containing protein 2, molybdenum cofactor sulfurase C-terminal domain-containing protein 2, MARC2, MOSC2,)
• NCBI Gene ID: 54996
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q969Z3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitochondrial amidoxime reducing component 2 interacts with:

• cytochrome c oxidase assembly factor COX14
  ring finger protein 123
  solute carrier family 25 member 46
  syntabulin
  translocase of outer mitochondrial membrane 22

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.