CCDC40, coiled-coil domain containing 40

CCDC40, coiled-coil domain containing 40

• This gene encodes a protein that is necessary for motile cilia function. It functions in correct left-right axis formation by regulating the assembly of the inner dynein arm and the dynein regulatory complexes, which control ciliary beat. Mutations in this gene cause ciliary dyskinesia type 15, a disorder due to defects in cilia motility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

• Gene Synonyms (coiled-coil domain-containing protein 40, CFAP172, CILD15, FAP172,)
• NCBI Gene ID: 55036
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q4G0X9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

coiled-coil domain containing 40 interacts with:

• centromere protein H
  family with sequence similarity 83 member D
  GTF2H2 family member C
  intraflagellar transport 122
  intraflagellar transport 43
  KIAA0319 like
  parkin coregulated
  POTE ankyrin domain family member I
  tetratricopeptide repeat domain 21B
  TNFAIP3 interacting protein 2
  transmembrane O-mannosyltransferase targeting cadherins 4
  VPS53 subunit of GARP complex

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.