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PACS1, phosphofurin acidic cluster sorting protein 1

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PACS1, phosphofurin acidic cluster sorting protein 1

  • This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008]

  • Gene Synonyms (MRD17, SHMS, phosphofurin acidic cluster sorting protein 1, PACS-1, cytosolic sorting protein PACS-1,)
  • NCBI Gene ID: 55690
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>A0A024R5H6
    UNIPROT ID#>>Q6VY07
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphofurin acidic cluster sorting protein 1 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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