PBK, PDZ binding kinase

PBK, PDZ binding kinase

• This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

• Gene Synonyms (CT84, HEL164, Nori-3, SPK, TOPK, lymphokine-activated killer T-cell-originated protein kinase, MAPKK-like protein kinase, T-LAK cell-originated protein kinase, cancer/testis antigen 84, epididymis luminal protein 164, serine/threonine protein kinase, spermatogenesis-related protein kinase,)
• NCBI Gene ID: 55872
• Species: Homo sapiens (Human)
• UNIPROT ID#>>V9HWH0
  UNIPROT ID#>>Q96KB5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PDZ binding kinase interacts with:

• arrestin domain containing 1
  centrosomal protein 126
  galectin 9B
  leucine rich repeat containing 47
  ligand of numb-protein X 1
  MSL complex subunit 1
  TAFA chemokine like family member 3
  TGFB induced factor homeobox 2 like Y-linked
  zinc finger and BTB domain containing 26
  zinc finger protein 414
  zinc finger protein 526

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.