TMX4, thioredoxin related transmembrane protein 4

TMX4, thioredoxin related transmembrane protein 4

• This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017]

• Gene Synonyms (DJ971N18.2, PDIA14, TXNDC13, thioredoxin-related transmembrane protein 4, protein disulfide isomerase family A, member 14, thioredoxin domain containing 13, thioredoxin domain-containing protein 13,)
• NCBI Gene ID: 56255
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H1E5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

thioredoxin related transmembrane protein 4 interacts with:

• adhesion G protein-coupled receptor G5
  family with sequence similarity 234 member B
  immunoglobulin superfamily member 8
  rhomboid domain containing 1
  synoviolin 1
  testis expressed 101
  testis expressed 29
  translocase of outer mitochondrial membrane 22
  vasorin
  zinc activated ion channel

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.