MMP26, matrix metallopeptidase 26

MMP26, matrix metallopeptidase 26

• Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme may degrade collagen type IV, fibronectin, fibrinogen, and beta-casein, and activate matrix metalloproteinase-9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The encoded protein may promote cell invasion in multiple human cancers. [provided by RefSeq, May 2016]

• Gene Synonyms (matrix metalloproteinase-26, MMP-26, endometase, matrilysin 2,)
• NCBI Gene ID: 56547
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NRE1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

matrix metallopeptidase 26 interacts with:

• contactin associated protein family member 3B
  peptide deformylase, mitochondrial
  ubiquinol-cytochrome c reductase complex assembly factor 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.