CYP26B1, cytochrome P450 family 26 subfamily B member 1

CYP26B1, cytochrome P450 family 26 subfamily B member 1

• This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

• Gene Synonyms (CYP26A2, P450RAI-2, P450RAI2, RHFCA, cytochrome P450 26B1, cytochrome P450 family 26 subfamily A member 1, cytochrome P450 retinoic acid-inactivating 2, cytochrome P450 retinoid metabolizing protein, cytochrome P450, family 26, subfamily B, polypeptide 1, cytochrome P450, subfamily XXVIB, polypeptide 1, retinoic acid-metabolizing cytochrome,)
• NCBI Gene ID: 56603
• Species: Homo sapiens (Human)
• UNIPROT ID#>>E7ER08
  UNIPROT ID#>>Q9NR63
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cytochrome P450 family 26 subfamily B member 1 interacts with:

• ring finger protein 123

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