MDM1, Mdm1 nuclear protein

MDM1, Mdm1 nuclear protein

• This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. Naturally-occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration. [provided by RefSeq, Feb 2019]

• Gene Synonyms (nuclear protein MDM1, Mdm4, transformed 3T3 cell double minute 1, p53 binding protein, nuclear protein double minute 1,)
• NCBI Gene ID: 56890
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TC05
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Mdm1 nuclear protein interacts with:

• coiled-coil domain containing 57
  POC1 centriolar protein A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.