POLD4, DNA polymerase delta 4, accessory subunit

POLD4, DNA polymerase delta 4, accessory subunit

• This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

• Gene Synonyms (POLDS, p12, DNA polymerase delta subunit 4, DNA polymerase delta smallest subunit p12, polymerase (DNA) delta 4, accessory subunit, polymerase (DNA-directed), delta 4, accessory subunit,)
• NCBI Gene ID: 57804
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HCU8
  UNIPROT ID#>>Q6NSD7
  UNIPROT ID#>>A0A024R5D7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DNA polymerase delta 4, accessory subunit interacts with:

• SprT-like N-terminal domain

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.