RTN2, reticulon 2

RTN2, reticulon 2

• This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012]

• Gene Synonyms (reticulon-2, NSP-like protein 1, NSP-like protein I, neuroendocrine-specific protein-like I, NSP2, NSPL1, NSPLI, SPG12,)
• NCBI Gene ID: 6253
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A8K7F2
  UNIPROT ID#>>Q6GMT0
  UNIPROT ID#>>O75298
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

reticulon 2 interacts with:

• ATPase Na+/K+ transporting family member beta 4
  inositol-pentakisphosphate 2-kinase
  junctophilin 1
  limb development membrane protein 1 like
  microspherule protein 1
  reticulon 4
  synaptophysin like 2
  tankyrase
  transmembrane protein 128
  vitronectin

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.