- Gene Overview
- Interaction Network
- Sequence Verification
SCN2A, sodium voltage-gated channel alpha subunit 2
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Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels function in the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. Allelic variants of this gene are associated with seizure disorders and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
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Gene Synonyms (sodium channel protein type 2 subunit alpha, sodium channel protein brain II subunit alpha, sodium channel protein type II subunit alpha, sodium channel protein, brain type 2 alpha subunit, sodium channel, voltage-gated, type II, alpha 1 polypeptide, sodium channel, voltage-gated, type II, alpha 2 polypeptide, sodium channel, voltage-gated, type II, alpha subunit, voltage-gated sodium channel subtype II, voltage-gated sodium channel subunit alpha Nav1.2, voltage-gated sodium channel type II alpha subunit, BFIC3, BFIS3, BFNIS, EA9, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2,)
- NCBI Gene ID:
6326
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q99250
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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sodium voltage-gated channel alpha subunit 2 interacts with:
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