CXCL5, C-X-C motif chemokine ligand 5

CXCL5, C-X-C motif chemokine ligand 5

• This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]

• Gene Synonyms (C-X-C motif chemokine 5, chemokine (C-X-C motif) ligand 5, epithelial-derived neutrophil-activating protein 78, neutrophil-activating peptide ENA-78, neutrophil-activating protein 78, small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78), ENA-78, SCYB5,)
• NCBI Gene ID: 6374
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P42830
  UNIPROT ID#>>Q6I9S7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

C-X-C motif chemokine ligand 5 interacts with:

• alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
  EGF containing fibulin extracellular matrix protein 2
  notch 2 N-terminal like A
  von Willebrand factor C domain containing 2 like

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.