SMOC2, SPARC related modular calcium binding 2

SMOC2, SPARC related modular calcium binding 2

• This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

• Gene Synonyms (SPARC-related modular calcium-binding protein 2, SMAP-2, SMOC-2, secreted modular calcium-binding protein 2, smooth muscle associated protein 2, thyroglobulin type-1 repeat containing protein, DTDP1, MST117, MSTP117, MSTP140, SMAP2, bA270C4A.1, bA37D8.1, dJ421D16.1,)
• NCBI Gene ID: 64094
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H3U7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SPARC related modular calcium binding 2 interacts with:

• keratin associated protein 5-1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.