ECSCR, endothelial cell surface expressed chemotaxis and apoptosis regulator

ECSCR, endothelial cell surface expressed chemotaxis and apoptosis regulator

• The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

• Gene Synonyms (ARIA, ECSM2, endothelial cell-specific chemotaxis regulator, apoptosis regulator through modulating IAP expression, endothelial cell-specific molecule 2,)
• NCBI Gene ID: 641700
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q19T08
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

endothelial cell surface expressed chemotaxis and apoptosis regulator interacts with:

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