SCG5, secretogranin V

SCG5, secretogranin V

• This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126). Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019]

• Gene Synonyms (neuroendocrine protein 7B2, pituitary polypeptide, prohormone convertase chaperone, secretogranin-5, secretory granule endocrine protein I, secretory granule, neuroendocrine protein 1 (7B2 protein), 7B2, P7B2, SGNE1, SgV,)
• NCBI Gene ID: 6447
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R9I1
  UNIPROT ID#>>P05408
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

secretogranin V interacts with:

• KH RNA binding domain containing, signal transduction associated 1
  nuclear receptor subfamily 1 group H member 2
  ubiquilin 1
  ubiquilin 2
  ubiquilin 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.