ALDH8A1, aldehyde dehydrogenase 8 family member A1

ALDH8A1, aldehyde dehydrogenase 8 family member A1

• This gene encodes a member of the aldehyde dehydrogenase family of proteins. The encoded protein has been implicated in the synthesis of 9-cis-retinoic acid and in the breakdown of the amino acid tryptophan. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. In addition, this enzyme has been shown to catalyze the conversion of 2-aminomuconic semialdehyde to 2-aminomuconate in the kynurenine pathway of tryptophan catabolism. [provided by RefSeq, Jul 2018]

• Gene Synonyms (2-aminomuconic semialdehyde dehydrogenase, aldehyde dehydrogenase 12, aldehyde dehydrogenase family protein, ALDH12, DJ352A20.2,)
• NCBI Gene ID: 64577
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H2A2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

aldehyde dehydrogenase 8 family member A1 interacts with:

• aminopeptidase like 1

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