PORCN, porcupine O-acyltransferase

PORCN, porcupine O-acyltransferase

• This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2013]

• Gene Synonyms (protein-serine O-palmitoleoyltransferase porcupine, porcupine homolog, probable protein-cysteine N-palmitoyltransferase porcupine, DHOF, FODH, MG61, PORC, PPN,)
• NCBI Gene ID: 64840
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H237
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

porcupine O-acyltransferase interacts with:

• CACN subunit beta associated regulatory protein
  Wnt family member 3A
  Wnt family member 5B

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