GPBP1, GC-rich promoter binding protein 1

GPBP1, GC-rich promoter binding protein 1

• This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

• Gene Synonyms (vasculin, vascular wall-linked protein, GPBP, SSH6, VASCULIN,)
• NCBI Gene ID: 65056
• Species: Homo sapiens (Human)
• UNIPROT ID#>>D4PHA4
  UNIPROT ID#>>Q86WP2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

GC-rich promoter binding protein 1 interacts with:

• coiled-coil domain containing 57
  egl-9 family hypoxia inducible factor 3
  FAM161 centrosomal protein A
  fibronectin type III domain containing 11
  hephaestin like 1
  leucine rich repeat containing 15
  lysophospholipase-like 1
  OTU deubiquitinase, ubiquitin aldehyde binding 2
  oxidoreductase NAD-binding domain containing 1
  pleckstrin homology and FYVE domain containing 2
  SLX1 homolog A, structure-specific endonuclease subunit
  TNFAIP3 interacting protein 2
  zinc finger and BTB domain containing 48

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.