RAPH1, Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

RAPH1, Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

• This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

• Gene Synonyms (ras-associated and pleckstrin homology domains-containing protein 1, amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 18, amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 9, lamellipodin, proline-rich EVH1 ligand 2, ALS2CR18, ALS2CR9, LPD, PREL-2, PREL2, RMO1, RalGDS/AF-6,)
• NCBI Gene ID: 65059
• Species: Homo sapiens (Human)
• UNIPROT ID#>>C9K0J5
  UNIPROT ID#>>Q70E73
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 interacts with:

• TATA-box binding protein associated factor 15

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