TBX2, T-box transcription factor 2

TBX2, T-box transcription factor 2

• This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (T-box transcription factor TBX2, T-box 2, T-box protein 2, VETD,)
• NCBI Gene ID: 6909
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13207
  UNIPROT ID#>>A0A024QZ86
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

T-box transcription factor 2 interacts with:

• ataxin 1 like
  cell death inducing DFFA like effector b
  cysteine rich tail 1
  keratin associated protein 6-3
  leucine zipper like transcription regulator 1
  TEA domain transcription factor 2
  tetratricopeptide repeat domain 19
  transportin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.