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TRPM2, transient receptor potential cation channel subfamily M member 2

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TRPM2, transient receptor potential cation channel subfamily M member 2

  • The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2016]

  • Gene Synonyms (transient receptor potential cation channel subfamily M member 2, estrogen-responsive element-associated gene 1 protein, long transient receptor potential channel 2, transient receptor potential channel 7, transient receptor potential melastatin 2, EREG1, KNP3, LTRPC2, LTrpC-2, NUDT9H, NUDT9L1, TRPC7,)
  • NCBI Gene ID: 7226
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>B4DVI8
    UNIPROT ID#>>O94759
    UNIPROT ID#>>Q14DR2
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transient receptor potential cation channel subfamily M member 2 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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